Cite: JAMA Intern Med. Published online February 27, 2023. doi:10.1001/jamainternmed.2023.0015
Question What is the association of cardiovascular health (CVH) levels, estimated by the American Heart Association’s Life’s Essential 8 score, with life expectancy free of major chronic diseases?
Findings In this cohort study of 135 199 adults from the UK Biobank study, high CVH level was associated with substantially longer life expectancy free of 4 major chronic diseases (cardiovascular disease, diabetes, cancer, and dementia) in both men and women. Furthermore, the disease-free life expectancy was similar between low and other socioeconomic groups among participants with high CVH.
Meaning These findings support improvement in population health by promoting a high CVH level, which may also narrow health disparities associated with socioeconomic status.
Author(s): Xuan Wang, MD, PhD1; Hao Ma, MD, PhD1; Xiang Li, MD, PhD1; et al
From March 1 through August 22, 2020, 146 557 deaths were recorded in California, with an estimated 19 806 (95% prediction interval, 16 364-23 210) deaths in excess of those predicted by historical trends (Table). Per capita excess mortality was highest among people aged 65 years and older, men, Black and Latino residents, and those without a college degree. Comparing deaths in March through April vs May through August, Latino residents and those without a high school degree or general education development (GED) certificate had the greatest increase in excess deaths, with Latino deaths tripling (from 16 to 51 excess deaths per million) and deaths in those without a high school degree/GED increasing by a factor of 3.4 (from 21 to 72 excess deaths per million). Across age groups, younger adults had the greatest increases in excess death, with rates more than doubling between shutdown and reopening (age, 25-54 years: from 4 to 11 excess deaths per million, 55-64 years: from 12 to 30 excess deaths per million).
In most weeks of the pandemic, Black residents had higher per capita excess mortality than other racial/ethnic group (Figure). Late in the shelter-in-place period, White, Asian, and Black residents had a decline in excess per capita mortality. In contrast, Latino residents and those without a high school degree/GED saw a substantial and sustained increase in per capita mortality.
Author(s): Yea-Hung Chen, PhD, MS1; M. Maria Glymour, ScD, MS2; Ralph Catalano, PhD, MRP3; et al