Pfizer Inc. and partner BioNTech SE said their Covid-19 vaccine was found to be safe in children ages 5 to 11 years in a late-stage study and generated a strong immune response in them, bringing the prospect of broader vaccination coverage closer.
Pfizer said it would share the results with regulators in the U.S. and other countries and seek emergency-use authorization in the U.S. as early as the end of the month.
The companies said the two-dose shot was found to be safe and well tolerated among the children in the study. The vaccine generated levels of antibodies that were similar to those of younger adults, meeting the study’s measurements of success, according to the companies.
Pfizer and BioNTech said they hadn’t yet determined vaccine efficacy — how well it protects against Covid-19 — for children in the age group. Not enough young subjects in the study have become sick to compare rates between children who got a vaccine and those who got a placebo, but researchers could still learn more as the trial continues.
Johnson & Johnson released data showing that a booster dose to its one-shot coronavirus vaccine provides a strong immune response months after people receive a first dose.
J&J said in statement Tuesday that it ran two early studies in people previously given its vaccine and found that a second dose produced an increased antibody response in adults from age 18 to 55. The study’s results haven’t yet been peer-reviewed.
On top of that, other research shows that since the vaccine first became available to health care workers in December 2020, the rate of vaccination among nurses and nursing home aides has been lower than that of physicians. This may be of particular concern because nurses and aides have such frequent and close contact with patients.
Data shows health care workers have gotten the COVID-19 vaccine at a higher rate than the general population: 73% versus 64% of non-health care workers. And many may assume that people who work in health care industry are more enthusiastic about the vaccine and less apprehensive.
While a majority of nurses are vaccinated and more than half support vaccine mandates in the workplace, some are pushing back against requirements to get vaccinated or face mandatory testing and say they would rather leave their jobs. And hospitals are already feeling the effects.
Uncertainty over future surges of COVID-19 and the end of regulatory flexibilities are going to be major drivers for 2022 premiums on the individual and small group markets, a new actuary report finds.
The report, released Thursday (PDF) by the American Academy of Actuaries, finds insurers face major uncertainties like the end of the public health emergency and the fate of enhanced subsidies for coverage on the Affordable Care Act’s (ACA’s) insurance exchanges.
“Greater degrees of uncertainty could lead to more conservative assumptions and risk margins for some insurers,” the report said. “Alternatively, carriers might lower risk margins, seeing an opportunity to capitalize on the increased enrollment due to the [American Rescue Plan Act] subsidies.”
Almost everyone I know in Britain has been surprised—for once, pleasantly so—by the success of the country’s vaccination program against Covid-19. We are so accustomed to the abject failure of our public administration in almost everything, from its political dithering, followed by self-evidently wrong (and costly) decisions, to its bureaucratic incompetence and moral corruption, that when something goes right, we stand amazed. What, indeed, can explain why something should at last have gone right?
The government decided that everyone should be immunized according to risk—first the oldest people and health workers, then the slightly less old and those with compromised immunity, and then the still less old, and so forth, until all adults will have been covered. By spring, more than half the population had received a first (and most important) dose of a vaccine. Almost no opposition to, or even criticism of, this manner of proceeding has arisen— unlike with almost everything else the government has done in its response to the pandemic—and the uptake of the vaccination offer has been high, except among some ethnic minority groups.
The government website to make a vaccination appointment could hardly have been better designed. It gave a large choice of locations, based on their distance from one’s home; we could select time and place. My wife and I chose the following day at noon at Ludlow Racecourse, where a large vaccination center was operating. We could have had our vaccination at my local doctors’ office, 300 hundred yards away from where we lived, but in a time of lockdown, we wanted a day out: so reduced have been our horizons of late that a drive of 20 miles or so seemed almost exciting.
Some people can blame their DNA for making them more likely to get COVID-19 or becoming severely ill if they get infected.
A study of more than 45,000 people with COVID-19 has uncovered 13 genetic variants linked to an increased risk of infection with SARS-CoV-2 or a higher chance of developing severe illness, researchers report July 8 in Nature. The team includes more than 3,300 researchers in 25 countries.
Some of the variants had been uncovered in previous studies. For instance, researchers again confirmed a genetic link between blood type and the likelihood of getting infected, but don’t know why people with type O blood may be slightly protected. The study also verified that a variant that disables the TYK2 gene raises the risk of critical illness and hospitalization. That variant is known to protect against autoimmune disease, but leaves people more vulnerable to tuberculosis.
President Biden on Thursday unveiled a series of steps to combat the newly surging pandemic, including the announcement of a forthcoming federal rule that all businesses with 100 or more employees have to ensure that every worker is either vaccinated for COVID-19 or submit to weekly testing for the coronavirus.
Among the other steps, Biden also announced that federal workers and contractors will be required to be vaccinated for COVID-19, eliminating an option laid out in July for unvaccinated employees to be regularly tested instead.
White House press secretary Jen Psaki said federal workers would have about 75 days to become fully vaccinated, once Biden signed an executive order later Thursday. She said there would be limited exemptions for religious or medical reasons.
Some federal agencies will require proof of vaccination while others will accept attestations, Psaki said. Workers who fail to comply with the requirement will be counseled by their human resources departments, and then will face “progressive disciplinary action,” she said.
Biden announced that 17 million health care workers at hospitals and other health care settings like dialysis clinics and home health agencies that receive Medicare or Medicaid funding will have to be vaccinated.
There will be similar requirements for teachers and staff at the Head Start early education program and other federally funded educational settings, such as schools on military bases.
How small are the chances of the average vaccinated American contracting Covid? Probably about one in 5,000 per day, and even lower for people who take precautions or live in a highly vaccinated community.
Or maybe one in 10,000
The estimates here are based on statistics from three places that have reported detailed data on Covid infections by vaccination status: Utah; Virginia; and King County, which includes Seattle, in Washington state. All three are consistent with the idea that about one in 5,000 vaccinated Americans have tested positive for Covid each day in recent weeks.
The chances are surely higher in the places with the worst Covid outbreaks, like the Southeast. And in places with many fewer cases — like the Northeast, as well as the Chicago, Los Angeles and San Francisco areas — the chances are lower, probably less than 1 in 10,000. That’s what the Seattle data shows, for example. (These numbers don’t include undiagnosed cases, which are often so mild that people do not notice them and do not pass the virus to anyone else.)
Here’s one way to think about a one-in-10,000 daily chance: It would take more than three months for the combined risk to reach just 1 percent.
According to data compiled by the Centers For Disease Control, approximately one in every 5,000 vaccinated Americans has tested positive for the coronavirus. That number is probably much lower in places with significantly fewer cases — like the Northeast, Chicago, Los Angeles, and San Francisco areas, where it is probably fewer than one in 10,000.
This is the first detailed data about so-called “breakthrough” infections — positive tests from people fully vaccinated. The data suggests that politicians and public health officials are wildly overreacting to the delta variant’s effect on the already vaccinated.
Wealthy, vaccine manufacturing countries like Germany, France, and the U.S. have pledged to fully vaccinate their own populations while also sharing doses with the developing world. But it’s not clear that a sufficient number of doses currently exist for them to make good on this promise. The European Union, for example, is on track to fall far short of its goal of donating 200 million doses to non-member states by the end of the year. And as of August, COVAX, the World Health Organization’s (WHO) vaccine sharing initiative, had distributed 188 million vaccines worldwide, just 19 percent of the 1.1 billion that the WHO says are needed to end the pandemic.
The more people remain unvaccinated worldwide, the likelier it is that new variants will emerge, endangering vaccinated and unvaccinated alike.
Legally, the U.S. may already have the ability to do so. The terms between Moderna and the federal government specify that the government possesses rights to the vaccine technology developed under the contract, meaning that it can unilaterally publish or share the data with anyone. Furthermore, an essential component of the Moderna vaccine was invented and patented by U.S. government researchers, meaning that the government could threaten a patent infringement suit against Moderna if the company refuses to share its vaccine know-how.
The Biden administration’s vaccination requirement is putting a squeeze on nursing homes as they try to balance protecting residents and retaining low-wage staff that have been reluctant to get the shot.
Later this month, the administration will outline a policy that requires all staff working at nursing homes to be vaccinated or risk the facilities losing federal funding.
The specifics of the policy are sparse so far, but it would effectively be a mandate for an industry that relies heavily on Medicare and Medicaid funding.https://aef67baff698e02f95a8ec2b0d53753d.safeframe.googlesyndication.com/safeframe/1-0-38/html/container.html
Only about 62 percent of nursing home and long term care facility staff are fully or partially vaccinated nationally, according to federal data compiled by the Centers for Medicare and Medicaid Services (CMS).
“The biggest group of unvaccinated staff are certified nurse aides. They’re making close to minimum wage. They can make that, maybe even more, plus maybe even better benefits out in retail jobs, restaurant jobs. The vast majority of those employers are not imposing mandates,” Grabowski said.