At the Medical University of South Carolina, nearly all fully vaccinated Covid-19 patients in the ICU have weak immune systems from prior health problems, said Andrew Goodwin, the section chief of critical care. The rest are elderly, which can also compromise the body’s defense against illness.
Truveta Inc., a firm that aggregates hospitals’ medical data for research, found among 1.7 million fully vaccinated people that those with diabetes, chronic lung disease and chronic kidney disease were about twice as likely to be hospitalized for breakthrough cases as vaccinated people without these conditions.
The likelihood of having a breakthrough infection was still low, though confirmed infections were more common for people with these illnesses. About 1.5% of roughly 110,000 people with chronic kidney disease had one, for example. But Truveta found about a quarter of breakthrough patients with chronic kidney disease wound up hospitalized. The likelihood of hospitalizations for people with breakthrough cases but without underlying health problems was about 7.5%.
Breakthrough deaths are hitting older people the hardest, amplifying a well-worn pandemic pattern. Exclusive data the Journal reviewed from the Epic Health Research Network, which analyzes data from the medical-record software company Epic Systems Corp., shows about 80% of breakthrough deaths among the vaccinated are in people ages 65 and older. The data included records for 19.5 million fully vaccinated people. Among all Covid-19 deaths this year, that age group represents closer to 69%, according to the CDC.
Author(s): Jon Kamp, Melanie Evans
Publication Date: 21 Nov 2021
Publication Site: Wall Street Journal